Russian ‘ successful ’ clone В 0 / W 148 of Mycobacterium tuberculosis Beijing genotype : 1 multiplex PCR assay for rapid detection and global screening
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چکیده
1 multiplex PCR assay for rapid detection and global screening 2 3 4 Igor Mokrousov*, Olga Narvskaya, Anna Vyazovaya, Tatiana Otten, Wei-Wei Jiao, Lia Lima 5 Gomes, Philip N. Suffys, A-Dong Shen, and Boris Vishnevsky 6 7 Laboratory of Molecular Microbiology, St. Petersburg Pasteur Institute ; Laboratory of Microbiology, 8 The Research Institute of Phthisiopulmonology , St. Petersburg, Russia; National Key Discipline of 9 Paediatrics, Key Laboratory of Major Diseases in Children (Capital Medical University), Ministry of 10 Education, Beijing Pediatric Research Institute, Beijing Children’s Hospital affiliated to Capital 11 Medical University, Beijing, China ; Laboratory of Molecular Biology Applied to Mycobacteria, 12 Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil 4 13 14 15 Running Title: M. TUBERCULOSIS BEIJING GENOTYPE 16 17
منابع مشابه
Russian "successful" clone B0/W148 of Mycobacterium tuberculosis Beijing genotype: a multiplex PCR assay for rapid detection and global screening.
We describe a multiplex PCR assay to detect the Mycobacterium tuberculosis Beijing genotype variant B0/W148, which is considered a "successful" clone of M. tuberculosis, widespread in Russia. Specificity and sensitivity of the assay were 100% based on the analysis of a collection of 516 M. tuberculosis isolates of different genotypes and origins. This assay may be used for accurate and simple d...
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تاریخ انتشار 2012